Modeling Membrane Protein–Ligand Binding Interactions: The Human Purinergic Platelet Receptor
نویسندگان
چکیده
منابع مشابه
Systematic prediction of human membrane receptor interactions.
Membrane receptor-activated signal transduction pathways are integral to cellular functions and disease mechanisms in humans. Identification of the full set of proteins interacting with membrane receptors by high-throughput experimental means is difficult because methods to directly identify protein interactions are largely not applicable to membrane proteins. Unlike prior approaches that attem...
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ژورنال
عنوان ژورنال: The Journal of Physical Chemistry B
سال: 2016
ISSN: 1520-6106,1520-5207
DOI: 10.1021/acs.jpcb.6b09535